Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

VEGFA rSNPs, transcriptional factor binding sites and human disease.

The journal of physiological sciences : JPS - 1 Jan 2014

Buroker Norman E

Abstract excerpt

Three regulatory SNPs (rSNPs) in the promoter region of the vascular endothelial growth factor-A (VEGFA) gene have been significantly associated with several human diseases or conditions. The rSNP alleles alter the DNA landscape for potential transcriptional factors to attach, resulting in changes in transcriptional factor binding sites (TFBS). These TFBS changes are examined with respect to the human diseases...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to Coronary Artery Disease
Share to Diabetic Retinopathy

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Disease

Share to IgA Vasculitis

Share to Promoter Regions, Genetic

Share to Transcription Factors

Share to Vascular Endothelial Growth Factor A

Source

Open in PubMed Open full text

Identifiers

PMID: 24097272
DOI: 10.1007/s12576-013-0293-4
PMCID: PMC10717560

Genes

VEGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

VEGFA rSNPs, transcriptional factor binding sites and human disease.PMID 24097272Read ↗

Regulatory SNPs and transcriptional factor binding sites in ADRBK1, AKT3, ATF3, DIO2, TBXA2R and VEGFA.Semantic proximity Read ↗

Regulatory SNPs: Altered Transcription Factor Binding Sites Implicated in Complex Traits and Diseases.Semantic proximity Read ↗

The distribution of SNPs in human gene regulatory regions.Semantic proximity Read ↗

Functional non-coding SNPs in human endothelial cells fine-map vascular trait associationsSemantic proximity Read ↗

SNP@Promoter: a database of human SNPs (single nucleotide polymorphisms) within the putative promoter regions.Semantic proximity Read ↗

Identification of cis- and trans-acting genetic variants explaining up to half the variation in circulating vascular endothelial growth factor levels.Semantic proximity Read ↗

[Polymorphisms in gene regulatory regions and their role in the physiopathology of complex disease in the post-genomic era].Semantic proximity Read ↗

Functional noncoding SNPs in human endothelial cells fine-map vascular trait associations.Semantic proximity Read ↗

How to Use SNP_TATA_Comparator to Find a Significant Change in Gene Expression Caused by the Regulatory SNP of This Gene's Promoter via a Change in Affinity of the TATA-Binding Protein for This Promoter.Semantic proximity Read ↗

Identifying functional single nucleotide polymorphisms in the human CArGome.Semantic proximity Read ↗

Transcriptional regulation of the VEGF gene in dependence of individual genomic variations.Semantic proximity Read ↗

Mechanism of allele specific assembly and disruption of master regulator transcription factor complexes of NF-KBp50, NF-KBp65 and HIF1a on a non-coding FAS SNP.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.