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Article

Multiple loci in the HLA complex are associated with Addison's disease.

The Journal of clinical endocrinology and metabolism - 1 Oct 2011

Skinningsrud Beate, Lie Benedicte A, Lavant Ewa, Carlson Joyce A, Erlich Henry, Akselsen Hanne E, Gervin Kristina, Wolff Anette B, Erichsen Martina M, Løvås Kristian, Husebye Eystein S, Undlien Dag E

Abstract excerpt

CONTEXT: A strong association between autoimmune Addison's disease (AAD) and major histocompatibility complex class II-encoded HLA-DRB1-DQA1-DQB1 haplotypes is well known. Recent evidence from other autoimmune diseases has suggested that class I-encoded HLA-A and HLA-B gene variants confer HLA-DRB1-DQA1-DQB1-independent effects on disease. OBJECTIVE: We aimed to explore AAD predisposing effects of HLA-A and -B...

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Share to Addison Disease
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21816777
DOI: 10.1210/jc.2011-0645

Genes

MICA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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