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Interleukin-26: An Emerging Player in Host Defense and Inflammation

20 Jul 2015

Abstract excerpt

The production of interleukin (IL)-26 was initially attributed to T cells, and in particular to Th17 cells. However, more recent findings indicate IL-26 production in natural killer (NK) cells, macrophages and fibroblast-like cells as well. It is known that IL-26 binds to the IL-20R1/IL-10R2 receptor complex on certain target cells, where it causes specific intracellular signaling and the secretion of IL-1β, IL-8...

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PMID: 26202572
DOI: 10.1159/000434646

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