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Article

IL‐36 cytokines and gut immunity

27 Jan 2021

Abstract excerpt

Interleukin 36 (IL-36) constitutes a group of cytokines that belong to the IL-1 superfamily. Emerging evidence has suggested a role of IL-36 in the pathogenesis of many inflammatory disorders. Intriguingly, in the gastrointestinal tract, IL-36 has a rather complex function. IL-36 receptor ligands are overexpressed in both animal colitis models and human IBD patients and may play both pathogenic and protective...

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PMID: 33501638
DOI: 10.1111/imm.13310

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