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Article

IL-27: a double agent in the IL-6 family.

Clinical and experimental immunology - 1 Jul 2018

Jones G W, Hill D G, Cardus A, Jones S A

Abstract excerpt

The cytokine interleukin (IL)-6 is a major therapeutic target for the treatment of various inflammatory and autoimmune diseases. While IL-6 receives considerable attention in studies of innate and adaptive immunity, the IL-6-related family member IL-27 is recognized increasingly for its effects on cellular proliferation, differentiation and leucocyte effector functions. Both cytokines activate responses in...

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Identifiers

PMID: 29437229
DOI: 10.1111/cei.13116
PMCID: PMC6037998

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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