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Article

A Genetic Variant in Pre-miR-146a (rs2910164 C>G) Is Associated with the Decreased Risk of Acute Coronary Syndrome in a Chinese Population.

The Tohoku journal of experimental medicine - 1 Nov 2015

Huang Suli, Lv Ziquan, Deng Qifei, Li Lu, Yang Binyao, Feng Jing, Wu Tangchun, Zhang Xiaomin, Cheng Jinquan

Abstract excerpt

MicroRNAs (miRNAs) can contribute to the development of cardiovascular diseases, and single nucleotide polymorphisms (SNPs) in miRNA genes may influence disease susceptibility by altering mature miRNA expression levels. However, the effect of SNPs located in miR-146a and miR-196a2 genes on risk of acute coronary syndrome (ACS) has not been reported in the Chinese population. Two miRNA polymorphisms located in...

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PMID: 26537765
DOI: 10.1620/tjem.237.227

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