Article
Combined Effects of PVT1 and MiR-146a Single Nucleotide Polymorphism on the Lung Function of Smokers with Chronic Obstructive Pulmonary Disease.
International journal of biological sciences - 1 Jan 2018
Zhou Sijing, Liu Yi, Li Min, Wu Peipei, Sun Gengyun, Fei Guanghe, Xu Xuan, Zhou Xuexin, Zhou Luqian, Wang Ran
Abstract excerpt
Non-coding RNAs play an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD). This study was performed to investigate the role of PVT1 and miR-146a single nucleotide polymorphisms (SNPs) in the lung function of COPD smokers. Real-time PCR and Western blot analyses were performed to measure the expression of miR-146 and PVT1 SNPs and determine the effect of these SNPs on the...
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