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Article

Population Difference in the Associations of KLOTH Promoter Methylation with Mild Cognitive Impairment in Xinjiang Uygur and Han Populations.

PloS one - 1 Jan 2015

Luo Mei, Zhou Xiaohui, Ji Huihui, Ma Wenjuan, Liu Guili, Dai Dongjun, Li Jingyun, Chang Lan, Xu Lei, Jiang Liting, Duan Shiwei, Wang Qinwen

Abstract excerpt

BACKGROUND: Mild cognitive impairment (MCI) is the intermediate stage of the cognitive changes between normal aging and dementia. KLOTH is an age-related gene that may contribute to the risk of MCI. The aim of our study was to explore the association between KLOTHO promoter methylation and MCI in Xinjiang Uygur and Han populations. METHODS: DNA methylation assay was performed using the bisulphite pyrosequencing...

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Identifiers

PMID: 26197428
DOI: 10.1371/journal.pone.0132156
PMCID: PMC4509908

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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