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[Analysis of genetic difference between mild cognitive impairment and Alzheimer's disease through genome-wide association study].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 10 Jun 2018

Bai Zhouxian, Kong Xiangdong

Abstract excerpt

OBJECTIVE: To explore the genetic difference between mild cognitive impairment (MCI) and Alzheimer's disease (AD) through association analysis of whole genome sequencing data. METHODS: Sequence data of 168 AD patients, 380 MCI patients and 261 elderly controls from the Alzheimer's Disease Neuroimaging Initiative (ADNI) project was collected. The genotype and phenotype association was analyzed through genome wide...

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PMID: 29896728
DOI: 10.3760/cma.j.issn.1003-9406.2018.03.008

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