Article
In vivo "MRI phenotyping" reveals changes in extracellular matrix transport and vascularization that mediate VEGF-driven increase in breast cancer metastasis.
PloS one - 1 Jan 2013
Pathak Arvind P, McNutt Stephen, Shah Tariq, Wildes Flonne, Raman Venu, Bhujwalla Zaver M
Abstract excerpt
PURPOSE: To gain new insights into the relationship between angiogenic factors in breast cancer and their effect on extracellular matrix (ECM) remodeling and metastasis, we characterized and validated the "metastatic signature" of human breast cancer cell lines engineered to overexpress VEGF in t...
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