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Article

Whole-exome sequencing in individuals with multiple cardiovascular risk factors and normal coronary arteries.

Coronary artery disease - 1 Jun 2016

Abramowitz Yigal, Roth Arie, Keren Gad, Isakov Ofer, Shomron Noam, Laitman Yael, Weissglas-Volkov Daphna, Arbel Yaron, Banai Shmuel, Finkelstein Ariel, Friedman Eitan

Abstract excerpt

OBJECTIVES: Most studies on the genes involved in coronary artery disease (CAD) targeted individuals with angiographically or clinically proven CAD. Focusing on high-risk individuals with normal coronary arteries (NCA) may offer novel insights into the pathogenesis of CAD. We aimed to identify genes putatively protective for development of CAD. METHODS: Pooled whole-exome sequencing (WES) was performed on 17...

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Source

Identifiers

PMID: 26905423
DOI: 10.1097/MCA.0000000000000357

Genes

CAD
ADAMTSL4
NID2
SPTBN5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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