Article
Three-dimensional co-culture of BM-MSCs and eccrine sweat gland cells in Matrigel promotes transdifferentiation of BM-MSCs.
Journal of molecular histology - 1 Oct 2015
Li Haihong, Li Xuexue, Zhang Mingjun, Chen Lu, Zhang Bingna, Tang Shijie, Fu Xiaobing
Abstract excerpt
Victims with extensive and deep burns are unable to regenerate eccrine sweat glands. Combining of stem cells and biomimetic ECM to generate cell-based 3D tissues is showing promise for tissue repair and regeneration. We co-cultured BrdU-labeled bone marrow-derived mesenchymal stem cells (BM-MSCs) and eccrine sweat gland cells in Matrigel for 2 weeks in vitro and then evaluated for BM-MSCs differentiation into...
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