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Article

Reduced cell cohesiveness of outgrowths from eccrine sweat glands delays wound closure in elderly skin

17 May 2016

Abstract excerpt

Human skin heals more slowly in aged vs. young adults, but the mechanism for this delay is unclear. In humans, eccrine sweat glands (ESGs) and hair follicles underlying wounds generate cohesive keratinocyte outgrowths that expand to form the new epidermis. Here, we compared the re-epithelialization of partial-thickness wounds created on the forearm of healthy young (< 40 yo) and aged (> 70 yo) adults. Our results...

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Share to Dermatologic Treatments and Research
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PMID: 27184009
DOI: 10.1111/acel.12493

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