Article
Non-skin mesenchymal cell types support epidermal regeneration in a mesenchymal stem cell or myofibroblast phenotype-independent manner.
Pathology international - 1 Jun 2009
Aoki Shigehisa, Takezawa Toshiaki, Uchihashi Kazuyoshi, Sugihara Hajime, Toda Shuji
Abstract excerpt
Skin-derived fibroblasts, preadipocytes and adipocytes, and non-skin-derived bone marrow stromal cells support epidermal regeneration. It remains unclear, however, whether various organ-derived mesenchymal cell (MC) types other than the aforementioned counterparts affect epidermal regeneration. Using a skin reconstruction model, it is shown here that heart-, spleen-, lung-, liver- and kidney-derived MC support...
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