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Article

Generation and Characterization of Induced Pluripotent Stem Cells from Patients with mtDNA Mutations.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2016

Hämäläinen Riikka H, Suomalainen Anu

Abstract excerpt

Generation of induced pluripotent stem cells from patient cells has revolutionized disease modeling in recent years. One research area, where disease models have previously been scarce, is disorders with mutations in mitochondrial DNA. These are a common cause for human disease and often cause very tissue specific phenotypes with vast clinical heterogeneity. iPS technology has now opened up new possibilities for...

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PMID: 26187202
DOI: 10.1007/7651_2015_258

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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