Article
Expression of an estrogen-regulated variant transcript of the peroxisomal branched chain fatty acid oxidase ACOX2 in breast carcinomas.
BMC cancer - 17 Jul 2015
Bjørklund Sunniva Stordal, Kristensen Vessela N, Seiler Michael, Kumar Surendra, Alnæs Grethe I Grenaker, Ming Yao, Kerrigan John, Naume Bjørn, Sachidanandam Ravi, Bhanot Gyan, Børresen-Dale Anne-Lise, Ganesan Shridar
Abstract excerpt
BACKGROUND: Alternate transcripts from a single gene locus greatly enhance the combinatorial flexibility of the human transcriptome. Different patterns of exon usage have been observed when comparing normal tissue to cancers, suggesting that variant transcripts may play a role in the tumor phenotype. METHODS: Ribonucleic acid-sequencing (RNA-seq) data from breast cancer samples was used to identify an intronic...
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