Article
SuhB is a novel ribosome associated protein that regulates expression of MexXY by modulating ribosome stalling in Pseudomonas aeruginosa.
Molecular microbiology - 1 Oct 2015
Shi Jing, Jin Yongxin, Bian Ting, Li Kewei, Sun Ziyu, Cheng Zhihui, Jin Shouguang, Wu Weihui
Abstract excerpt
Translation elongation is modulated by various ribosome-binding proteins. Environmental stresses, such as starvation and antibiotics, can cause stalling of bacterial ribosomes, which may alter gene expression through a transcription or translation attenuation mechanism. In Pseudomonas aeruginosa, the expression of MexXY multidrug efflux system, which plays a significant role in resistance against aminoglycoside...
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