Article

Sucrose-mediated translational stalling involves a conserved ribosomal pocket

2023-08-27

Abstract excerpt

Within eukaryotes, 20-50% of the mRNAs contain short open reading frames (uORFs) located upstream of the main ORF. A significant fraction of these uORFs encode conserved peptides (CPuORFs) that regulate translation in response to specific metabolites. A well-studied example includes uORF2 of the plant growth inhibiting transcription factor bZIP11. Elevated intracellular sucrose levels lead to ribosome stalling at...

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Literature Corpus work: c3c7c783-5231-530e-896c-3427e3870e6e
DOI: 10.1101/2023.08.27.554957

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