Article
High levels of TSP1+/CD142+ platelet-derived microparticles characterise young patients with high cardiovascular risk and subclinical atherosclerosis.
Thrombosis and haemostasis - 25 Nov 2015
Suades Rosa, Padró Teresa, Alonso Rodrigo, Mata Pedro, Badimon Lina
Abstract excerpt
Circulating microparticles (cMPs) play important roles in cellular crosstalk and are messengers of cell activation. We have previously reported that platelet-released microparticles (pMPs) stimulate thrombosis and that lipid-lowering treatment as per guidelines in patients with familial hypercholesterolaemia (FH) is not sufficiently effective in reducing pro-inflammatory cell activation and, consequently,...
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