Article
Circulating CD45+/CD3+ lymphocyte-derived microparticles map lipid-rich atherosclerotic plaques in familial hypercholesterolaemia patients.
Thrombosis and haemostasis - 1 Jan 2014
Suades Rosa, Padró Teresa, Alonso Rodrigo, López-Miranda José, Mata Pedro, Badimon Lina
Abstract excerpt
Circulating microparticles (cMPs) seem to play important roles in vascular function. Beyond markers of activated cells, cMPs may have potential paracrine functions and influence atherosclerosis. Here, our objective was to characterise a) the abundance and phenotype of cMPs in stable statin-treated heterozygous familial hypercholesterolaemia (FH) patients exposed to life-long hypercholesterolaemia and b) the...
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