Article
Growing thrombi release increased levels of CD235a(+) microparticles and decreased levels of activated platelet-derived microparticles. Validation in ST-elevation myocardial infarction patients.
Journal of thrombosis and haemostasis : JTH - 1 Oct 2015
Suades R, Padró T, Vilahur G, Martin-Yuste V, Sabaté M, Sans-Roselló J, Sionis A, Badimon L
Abstract excerpt
BACKGROUND: Local fluid dynamics and exposed atherosclerotic lesions regulate thrombus formation. Activated cells in the attached thrombi release microparticles to the circulation (circulating microparticles [cMPs]); however, their phenotype is unknown. OBJECTIVES: To investigate the specific phenotype of the cMPs released by growing thrombi. METHODS/PATIENTS: cMPs released by thrombi growing in different...
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