Article

Extracellular vesicles from monocyte/platelet aggregates modulate human atherosclerotic plaque responses

2019-11-13

Abstract excerpt

In atherosclerosis, a chronic disease characterized by lipid accumulation, fibrosis and vascular inflammation, extracellular vesicles (EVs) are emerging as key players in different stages of disease development. Here we provide evidence that EVs released by mixed aggregates of monocytes and platelets in response to TNF-α are both CD14+ and CD41+. Tempering platelet activation with Iloprost™ impacted the quality an...

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Identifiers and source

Literature Corpus work: 517da0f6-bf38-5f5e-a3bf-adc88719c376
DOI: 10.1101/841361

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