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Article

Differences in the Genetic Susceptibility to Age-Related Macular Degeneration Clinical Subtypes.

Investigative ophthalmology & visual science - 1 Jul 2015

Shen Ling, Hoffmann Thomas J, Melles Ronald B, Sakoda Lori C, Kvale Mark N, Banda Yambazi, Schaefer Catherine, Risch Neil, Jorgenson Eric

Abstract excerpt

PURPOSE: We compared across age-related macular degeneration (AMD) subtypes the effect of AMD risk variants, their predictive power, and heritability. METHODS: The prevalence of AMD was estimated among active non-Hispanic white Kaiser Permanente Northern California members who were at least 65 years of age as of June 2013. The genetic analysis included 5,170 overall AMD cases ascertained from electronic health...

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Identifiers

PMID: 26176866
DOI: 10.1167/iovs.15-16533
PMCID: PMC4509058

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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