Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of polymorphisms in complement component C3 gene with susceptibility to systemic lupus erythematosus.

Rheumatology (Oxford, England) - 1 Feb 2008

Miyagawa H, Yamai M, Sakaguchi D, Kiyohara C, Tsukamoto H, Kimoto Y, Nakamura T, Lee J-H, Tsai C-Y, Chiang B-L, Shimoda T, Harada M, Tahira T, Hayashi K, Horiuchi T

Abstract excerpt

OBJECTIVE: Identification of the genes responsible for systemic lupus erythematosus (SLE). METHODS: All the exons and putative promoter regions of 53 candidate genes (TNFRSF6/Fas, TNFSF6/FasL, Fli1, TNFSF10/TRAIL, TNFSF12/TWEAK, Bcl-2, PTEN, FADD, TRADD, CDKN1A, TNFRSF1A/TNFR1, TNFRSF4/OX40, TNFSF4/OX40L, TNFSF5/CD40L, TNFSF13B/BAFF, ICOS, CTLA4, CD28, FYN, G2A, CR2, PTPRC/CD45, CD22, CD19, Lyn, PDCD1, PTPN6,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Complement C3
Share to Complement System Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Interleukins

Share to Lupus Erythematosus, Systemic

Share to Polymorphism, Single-Stranded Conformational

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 18174230
DOI: 10.1093/rheumatology/kem321

Genes

APCS
CTLA4
DNASE1
FADD
FYN
ICOS
IFNG
MBL2
MERTK
PDCD1
PTEN
PTPN6
PTPRC
TGFB1
TGFB2
TGFB3
TGFBR1
TGFBR2
TGFBR3
TNFRSF4
TNFSF10
TNFSF11
TNFSF12
TNFSF4
TRADD

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of polymorphisms in complement component C3 gene with susceptibility to systemic lupus erythematosus.PMID 18174230Read ↗

Association between complement gene polymorphisms and systemic lupus erythematosus: a systematic review and meta-analysis.Semantic proximity Read ↗

Recent insights into the genetic basis of systemic lupus erythematosus.Semantic proximity Read ↗

Genetic association of complement component 2 polymorphism with systemic lupus erythematosus.Semantic proximity Read ↗

The intricate role of complement component C4 in human systemic lupus erythematosus.Semantic proximity Read ↗

Analysis of WDFY4 rs7097397 and PHLDB1 rs7389 polymorphisms in Chinese patients with systemic lupus erythematosus.Semantic proximity Read ↗

Association Between C1q, TRAIL, and Tim-1 Gene Polymorphisms and Systemic Lupus Erythematosus.Semantic proximity Read ↗

Autoimmune risk loci of IL12RB2, IKZF1, XKR6, TMEM39A and CSK in Chinese patients with systemic lupus erythematosus.Semantic proximity Read ↗

Comprehensive Assessment of the Association between FCGRs polymorphisms and the risk of systemic lupus erythematosus: Evidence from a Meta-Analysis.Semantic proximity Read ↗

Associations between TNFSF4 and TRAF1-C5 gene polymorphisms and systemic lupus erythematosus: a meta-analysis.Semantic proximity Read ↗

A meta-analysis of the association of IL-6 -174 G/C and -572 G/C polymorphisms with systemic lupus erythematosus risk.Semantic proximity Read ↗

Polymorphisms in FCN genes and their influence on systemic lupus erythematosus susceptibility: a report from Western India.Semantic proximity Read ↗

Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.