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Article

Analysis of CD8+ Treg cells in patients with ovarian cancer: a possible mechanism for immune impairment.

Cellular & molecular immunology - 1 Sept 2015

Zhang Shuping, Ke Xing, Zeng Suyun, Wu Meng, Lou Jianfang, Wu Lei, Huang Peijun, Huang Lei, Wang Fang, Pan Shiyang

Abstract excerpt

Regulatory T (Treg) cells may participate in mediating a suppressive microenvironment that blunts successful anti-tumor immunotherapy. Recent studies show that CD8(+) Treg cells might impede effective immune responses to established tumors. However, there is limited research regarding CD8(+) Treg cells in ovarian cancer (OC) patients. Here, we investigated CD8(+) Treg cells in OC patients and their in vitro...

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Identifiers

PMID: 26166762
DOI: 10.1038/cmi.2015.57
PMCID: PMC4579658

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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