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Article

Induced and natural regulatory T cells in human cancer.

Expert opinion on biological therapy - 1 Oct 2012

Whiteside Theresa L, Schuler Patrick, Schilling Bastian

Abstract excerpt

INTRODUCTION: Evidence suggests that FOXP3(+)CD25(high)CD4(+) regulatory T cells (Treg) which accumulate in cancer may have beneficial or unfavorable effects on prognosis. The presence in tumor-associated inflammatory infiltrates of two subsets of Treg with distinct phenotypic and functional profiles might explain these conflicting observations. AREAS COVERED: Human inducible (i) Treg arising by tumor-driven...

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Source

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Identifiers

PMID: 22849383
DOI: 10.1517/14712598.2012.707184
PMCID: PMC3730844

Genes

FOXP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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