Article
Regulatory T Cells Exhibit Distinct Features in Human Breast Cancer.
Immunity - 15 Nov 2016
Plitas George, Konopacki Catherine, Wu Kenmin, Bos Paula D, Morrow Monica, Putintseva Ekaterina V, Chudakov Dmitriy M, Rudensky Alexander Y
Abstract excerpt
Regulatory T (Treg) cells reside in lymphoid organs and barrier tissues where they control different types of inflammatory responses. Treg cells are also found in human cancers, and studies in animal models suggest that they contribute to cancer progression. However, properties of human intratumoral Treg cells and those present in corresponding normal tissue remain largely unknown. Here, we analyzed features of...
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