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Article

Identification of a novel mutation of the FLT3 gene located on the juxtamembrane domain from acute myeloid leukemia patients.

Molecular biology reports - 29 Jul 2024

Arwanih Elly Yanah, Rinaldi Ikhwan, Wanandi Septelia Inawati, Louisa Melva

Abstract excerpt

BACKGROUND: FLT3 gene mutations are genetic abnormality that caused leukemogenesis. Furthermore, presence of FLT3 mutations is associated with poor prognosis in AML. This study aimed to identify FLT3 gene mutations so that it can be used as a genetic reference for the AML patients in Indonesian population. METHODS: This cross-sectional study recruited 63 AML de novo patients between August 2021 and July 2023 at...

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PMID: 39073493
DOI: 10.1007/s11033-024-09790-1

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