Article
Functional characterization of two SOS-regulated genes involved in mitomycin C resistance in Caulobacter crescentus.
DNA repair - 1 Sept 2015
Lopes-Kulishev Carina O, Alves Ingrid R, Valencia Estela Y, Pidhirnyj María I, Fernández-Silva Frank S, Rodrigues Ticiane R, Guzzo Cristiane R, Galhardo Rodrigo S
Abstract excerpt
The SOS response is a universal bacterial regulon involved in the cellular response to DNA damage and other forms of stress. In Caulobacter crescentus, previous work has identified a plethora of genes that are part of the SOS regulon, but the biological roles of several of them remain to be determined. In this study, we report that two genes, hereafter named mmcA and mmcB, are involved in the defense against DNA...
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