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Article

Polymorphisms in alternative splicing associated genes are associated with lung cancer risk in a Chinese population.

Lung cancer (Amsterdam, Netherlands) - 1 Sept 2015

Shen Wei, Yin Rong, Wang Cheng, Zhu Meng, Zhou Wen, Qin Na, Sun Jie, Liu Jia, Dong Jing, Jin Guangfu, Ma Hongxia, Hu Zhibin, Shen Hongbing, Xu Lin, Dai Juncheng

Abstract excerpt

BACKGROUND: Alternative splicing is an important biological step during mRNA processing. Misregulation of alternative splicing can produce aberrant protein isoforms, thus contributing to cancer. We hypothesized that variants in 5 critical splicing factor-associated genes might play an important role in carcinogenesis of lung cancer. MATERIALS AND METHODS: A case-control study including 1,341 non-small cell lung...

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Identifiers

PMID: 26162562
DOI: 10.1016/j.lungcan.2015.06.010

Genes

PTBP2
SRSF7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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