Article
Genetic variants in chromatin-remodeling pathway associated with lung cancer risk in a Chinese population.
Gene - 10 Aug 2016
Geng Liguo, Zhu Meng, Wang Yuzhuo, Cheng Yang, Liu Jia, Shen Wei, Li Zhihua, Zhang Jiahui, Wang Cheng, Jin Guangfu, Ma Hongxia, Shen Hongbing, Hu Zhibin, Dai Juncheng
Abstract excerpt
Chromatin remodeling complexes utilize the energy of ATP hydrolysis to remodel nucleosomes and have essential roles in transcriptional modulation. Increasing evidences indicate that these complexes directly interact with numerous proteins and regulate the formation of cancer. However, few studies reported the association of polymorphisms in chromatin remodeling genes and lung cancer. We hypothesized that variants...
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