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Article

Direct Estimates of the Genomic Contributions to Blood Pressure Heritability within a Population-Based Cohort (ARIC).

PloS one - 1 Jan 2015

Salfati Elias, Morrison Alanna C, Boerwinkle Eric, Chakravarti Aravinda

Abstract excerpt

Blood pressure (BP) is a heritable trait with multiple environmental and genetic contributions, with current heritability estimates from twin and family studies being ~ 40%. Here, we use genome-wide polymorphism data from the Atherosclerosis Risk in Communities (ARIC) study to estimate BP heritability from genomic relatedness among cohort members. We utilized data on 6,365,596 and 9,578,528 genotyped and imputed...

Topics

Black People
Blood Pressure
Diastole
Female
Gene Frequency
Genetic Predisposition to Disease
Genome, Human
Humans
Inheritance Patterns
Male
Molecular Sequence Annotation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Systole

White People

Source

Open in PubMed Open full text

Identifiers

PMID: 26162070
DOI: 10.1371/journal.pone.0133031
PMCID: PMC4498745

Genes

DBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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