Causal relevance of different blood pressure traits on risk of cardiovascular diseases: GWAS and Mendelian randomisation in 100,000 Chinese adults.

doi:10.1038/s41467-024-50297-x

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Causal relevance of different blood pressure traits on risk of cardiovascular diseases: GWAS and Mendelian randomisation in 100,000 Chinese adults.

Nature communications - 24 Jul 2024

Pozarickij Alfred, Gan Wei, Lin Kuang, Clarke Robert, Fairhurst-Hunter Zammy, Koido Masaru, Kanai Masahiro, Okada Yukinori, Kamatani Yoichiro, Bennett Derrick, Du Huaidong, Chen Yiping, Yang Ling, Avery Daniel, Guo Yu, Yu Min, Yu Canqing, Schmidt Valle Dan, Lv Jun, Chen Junshi, Peto Richard, Collins Rory, Li Liming, Chen Zhengming, Millwood Iona Y, Walters Robin G

Abstract excerpt

Elevated blood pressure (BP) is major risk factor for cardiovascular diseases (CVD). Genome-wide association studies (GWAS) conducted predominantly in populations of European ancestry have identified >2,000 BP-associated loci, but other ancestries have been less well-studied. We conducted GWAS of systolic, diastolic, pulse, and mean arterial BP in 100,453 Chinese adults. We identified 128 non-overlapping loci...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Pressure

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cardiovascular Diseases

Share to China

Share to East Asian People

Share to Genome-Wide Association Study

Share to Hypertension

Share to Mendelian Randomization Analysis

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 39048560
DOI: 10.1038/s41467-024-50297-x
PMCID: PMC11269703

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Causal relevance of different blood pressure traits on risk of cardiovascular diseases: GWAS and Mendelian randomisation in 100,000 Chinese adults.PMID 39048560Read ↗

Causal relevance of different blood pressure traits on risk of cardiovascular diseases: GWAS and Mendelian randomisation in 100,000 Chinese adultsSemantic proximity Read ↗

Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk.Semantic proximity Read ↗

Genetic Variation in Blood Pressure and Lifetime Risk of Peripheral Artery Disease: A Mendelian Randomization StudySemantic proximity Read ↗

Genetic analysis of over one million people identifies 535 novel loci for blood pressureSemantic proximity Read ↗

Heritability and genome‐wide association study of blood pressure in Chinese adult twinsSemantic proximity Read ↗

Genome-wide analysis in over 1 million individuals reveals over 2,000 independent genetic signals for blood pressureSemantic proximity Read ↗

Direct Estimates of the Genomic Contributions to Blood Pressure Heritability within a Population-Based Cohort (ARIC).Semantic proximity Read ↗

Over 1000 genetic loci influencing blood pressure with multiple systems and tissues implicatedSemantic proximity Read ↗

Blood Pressure Genetics in Han Taiwanese With Cross-Trait Analysis in East Asians: Insights Into Comorbidities, All-Cause Mortality, and Cardiovascular MortalitySemantic proximity Read ↗

Genome-wide association analysis of pulse wave velocity traits provide new insights into the causal relationship between arterial stiffness and blood pressure.Semantic proximity Read ↗

Blood Pressure and Risk of Cardiovascular Disease in UK Biobank: A Mendelian Randomization Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.