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Article

Global Individual Ancestry Using Principal Components for Family Data.

Human heredity - 1 Jan 2015

de Andrade Mariza, Ray Debashree, Pereira Alexandre C, Soler Júlia P

Abstract excerpt

Studies of complex human diseases and traits associated with candidate genes are potentially vulnerable to bias (confounding) due to population stratification and inbreeding, especially in admixed population. In GWAS, the principal components (PCs) method provides a global ancestry value per subject, allowing corrections for population stratification. However, these coefficients are typically estimated assuming...

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PMID: 26159893
DOI: 10.1159/000381908
PMCID: PMC4583840

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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