Article
TCF21 hypermethylation in genetically quiescent clear cell sarcoma of the kidney.
Oncotarget - 30 Jun 2015
Gooskens Saskia L, Gadd Samantha, Guidry Auvil Jaime M, Gerhard Daniela S, Khan Javed, Patidar Rajesh, Meerzaman Daoud, Chen Qing-Rong, Hsu Chih Hao, Yan Chunhua, Nguyen Cu, Hu Ying, Mullighan Charles G, Ma Jing, Jennings Lawrence J, de Krijger Ronald R, van den Heuvel-Eibrink Marry M, Smith Malcolm A, Ross Nicole, Gastier-Foster Julie M, Perlman Elizabeth J
Abstract excerpt
Clear Cell Sarcoma of the Kidney (CCSK) is a rare childhood tumor whose molecular pathogenesis remains poorly understood. We analyzed a discovery set of 13 CCSKs for changes in chromosome copy number, mutations, rearrangements, global gene expression and global DNA methylation. No recurrent segmental chromosomal copy number changes or somatic variants (single nucleotide or small insertion/deletion) were...
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