Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutually exclusive BCOR internal tandem duplications and YWHAE-NUTM2 fusions in clear cell sarcoma of kidney: not the full story.

The Journal of pathology - 1 Apr 2016

Kenny Colin, Bausenwein Sabrina, Lazaro Antonio, Furtwängler Rhoikos, Gooskens Saskia L M, van den Heuvel Eibrink Marry, Vokuhl Christian, Leuschner Ivo, Graf Norbert, Gessler Manfred, O'Sullivan Maureen J

Abstract excerpt

Internal tandem duplication within the BCOR gene sequence that encodes the PUFD domain, important in the formation of the non-canonical or variant polycomb repressor complex 1 (v-PRC1), was very recently described in 100% of 20 clear cell sarcomas of kidney (CCSKs). None of those 20 cases bore the YWHAE-NUTM2 transcript, previously described by us in CCSK, and which constitutes the only other recurrent genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Gene Duplication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Fusion

Share to Kidney Neoplasms

Share to Prognosis

Share to Proto-Oncogene Proteins

Share to Repressor Proteins

Share to Tandem Repeat Sequences

Source

Identifiers

PMID: 27000436
DOI: 10.1002/path.4693

Genes

BCOR
YWHAE
PRC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutually exclusive BCOR internal tandem duplications and YWHAE-NUTM2 fusions in clear cell sarcoma of kidney: not the full story.PMID 27000436Read ↗

BCOR internal tandem duplication and YWHAE-NUTM2B/E fusion are mutually exclusive events in clear cell sarcoma of the kidney.Semantic proximity Read ↗

Recurrent internal tandem duplications of BCOR in clear cell sarcoma of the kidney.Semantic proximity Read ↗

Clear cell sarcomas of the kidney are characterised by <i><scp>BCOR</scp></i> gene abnormalities, including exon 15 internal tandem duplications and <i><scp>BCOR</scp>–<scp>CCNB</scp>3</i> gene fusionSemantic proximity Read ↗

Clear cell sarcoma of the kidney demonstrates an embryonic signature indicative of a primitive nephrogenic origin.Semantic proximity Read ↗

Recurrent BCOR Internal Tandem Duplication and YWHAE-NUTM2B Fusions in Soft Tissue Undifferentiated Round Cell Sarcoma of InfancySemantic proximity Read ↗

Aberrant epigenetic regulation in clear cell sarcoma of the kidney featuring distinct DNA hypermethylation and EZH2 overexpressionSemantic proximity Read ↗

Pediatric BCOR-Altered Tumors From Soft Tissue/Kidney Display Specific DNA Methylation ProfilesSemantic proximity Read ↗

BCOR Overexpression Is a Highly Sensitive Marker in Round Cell Sarcomas With BCOR Genetic AbnormalitiesSemantic proximity Read ↗

The clinical phenotype of YWHAE-NUTM2B/E positive pediatric clear cell sarcoma of the kidney.Semantic proximity Read ↗

Paediatric BCOR-associated sarcomas with a novel long spliced internal tandem duplication of BCOR exon 15.Semantic proximity Read ↗

PBRM1, SETD2 and BAP1 - the trinity of 3p in clear cell renal cell carcinoma.Semantic proximity Read ↗

A Pan-Cancer Landscape Analysis Reveals a Subset of Endometrial Stromal and Pediatric Tumors Defined by Internal Tandem Duplications of BCORSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.