Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BCOR internal tandem duplication and YWHAE-NUTM2B/E fusion are mutually exclusive events in clear cell sarcoma of the kidney.

Genes, chromosomes & cancer - 1 Feb 2016

Karlsson Jenny, Valind Anders, Gisselsson David

Abstract excerpt

Clear cell sarcoma of the kidney (CCSK) is the second most common pediatric renal tumor. Two recurrent genetic aberrations have been described in CCSK. One is a fusion of YWHAE and NUTM2B/E, the other is an internal tandem duplication (ITD) in the BCOR gene. Here it is shown that YWHAE-NUTM2B/E fusion and the BCOR ITD are mutually exclusive events and activated different downstream signaling systems. This has...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 14-3-3 Proteins
Share to Chromosome Duplication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kidney Neoplasms

Share to Oncogene Proteins, Fusion

Share to Proto-Oncogene Proteins

Share to Sequence Analysis, RNA

Share to Serine Endopeptidases

Share to Tandem Repeat Sequences

Source

Identifiers

PMID: 26493387
DOI: 10.1002/gcc.22316

Genes

BCOR
YWHAE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BCOR internal tandem duplication and YWHAE-NUTM2B/E fusion are mutually exclusive events in clear cell sarcoma of the kidney.PMID 26493387Read ↗

Clear cell sarcomas of the kidney are characterised by <i><scp>BCOR</scp></i> gene abnormalities, including exon 15 internal tandem duplications and <i><scp>BCOR</scp>–<scp>CCNB</scp>3</i> gene fusionSemantic proximity Read ↗

Mutually exclusive BCOR internal tandem duplications and YWHAE-NUTM2 fusions in clear cell sarcoma of kidney: not the full story.Semantic proximity Read ↗

Recurrent internal tandem duplications of BCOR in clear cell sarcoma of the kidney.Semantic proximity Read ↗

The clinical phenotype of YWHAE-NUTM2B/E positive pediatric clear cell sarcoma of the kidney.Semantic proximity Read ↗

Recurrent BCOR Internal Tandem Duplication and YWHAE-NUTM2B Fusions in Soft Tissue Undifferentiated Round Cell Sarcoma of InfancySemantic proximity Read ↗

Clear cell sarcoma of the kidney demonstrates an embryonic signature indicative of a primitive nephrogenic origin.Semantic proximity Read ↗

The expanding universe of NUTM1 fusions in pediatric cancerSemantic proximity Read ↗

Aberrant epigenetic regulation in clear cell sarcoma of the kidney featuring distinct DNA hypermethylation and EZH2 overexpressionSemantic proximity Read ↗

Paediatric BCOR-associated sarcomas with a novel long spliced internal tandem duplication of BCOR exon 15.Semantic proximity Read ↗

BCOR Overexpression Is a Highly Sensitive Marker in Round Cell Sarcomas With BCOR Genetic AbnormalitiesSemantic proximity Read ↗

Clear cell sarcoma of the kidney: a review.Semantic proximity Read ↗

Pediatric Renal Tumors: Updates in the Molecular Era.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.