Article
γδ T cells and epigenetic drugs: A useful merger in cancer immunotherapy?
22 May 2015
Abstract excerpt
γδ T cell-based immunotherapeutic strategies in cancer patients are as yet of limited success. Drugs targeting epigenetic mechanisms including histone acetylation and DNA methylation trigger cell death in tumor cells but in addition have immunomodulatory activity. Here, we discuss the potential benefit of combining both strategies in cancer immunotherapy.
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