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Article

Inhibition of Lactate Dehydrogenase to Treat Epilepsy

8 Jul 2015

Abstract excerpt

In vitro and in vivo studies show that levels of lactate available to neurons affects susceptibility to epileptic seizure, a finding consistent with the beneficial effect of a ketogenic diet to treat intractable epilepsy in humans.

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Identifiers

PMID: 26154793
DOI: 10.1056/nejmcibr1503558

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