Article
Modelling the Interplay between Lifestyle Factors and Genetic Predisposition on Markers of Type 2 Diabetes Mellitus Risk.
PloS one - 1 Jan 2015
Walker Celia G, Solis-Trapala Ivonne, Holzapfel Christina, Ambrosini Gina L, Fuller Nicholas R, Loos Ruth J F, Hauner Hans, Caterson Ian D, Jebb Susan A
Abstract excerpt
The risk of developing type 2 diabetes mellitus (T2DM) is determined by a complex interplay involving lifestyle factors and genetic predisposition. Despite this, many studies do not consider the relative contributions of this complex array of factors to identify relationships which are important in progression or prevention of complex diseases. We aimed to describe the integrated effect of a number of lifestyle...
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