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Effect of Diet Quality and Genetic Predisposition on Hemoglobin A1c and Type 2 Diabetes Risk: Gene-Diet Interaction Analysis of 357,419 Individuals.

Diabetes care - 1 Nov 2021

Zhuang Pan, Liu Xiaohui, Li Yin, Wan Xuzhi, Wu Yuqi, Wu Fei, Zhang Yu, Jiao Jingjing

Abstract excerpt

OBJECTIVE: To assess the interactions between diet quality and genetic predisposition to incident type 2 diabetes (T2D). RESEARCH DESIGN AND METHODS: Between 2006 and 2010, 357,419 participants with genetic and complete dietary data from the UK Biobank were enrolled and prospectively followed up to 2017. The genetic risk score (GRS) was calculated on the basis of 424 variants associated with T2D risk, and a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34433621
DOI: 10.2337/dc21-1051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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