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Article

Temporal changes and genetic susceptibility to type 2 diabetes (1984-2019; HUNT): a longitudinal, population-based study.

The lancet. Diabetes & endocrinology - 1 Mar 2026

Bjarkø Vera Vik, Wolford Brooke N, Haug Eirin B, Stene Lars C, Carlsson Sofia, Langhammer Arnulf, Birkeland Kåre I, Berg Tore Julsrud, Sørgjerd Elin Pettersen, Lyssenko Valeriya, Brumpton Ben M, Vie Gunnhild Åberge, Åsvold Bjørn Olav

Abstract excerpt

BACKGROUND: The global prevalence of type 2 diabetes has nearly doubled between 1990 and 2020. Genetic susceptibility confers increased risk of type 2 diabetes, but environmental exposures could modify this risk. We aimed to investigate how societal changes have affected the prevalence of type 2 diabetes in people with high and low genetic susceptibility, using chronological time as an indicator for these...

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PMID: 41619756
DOI: 10.1016/S2213-8587(25)00322-5

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