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Article

Meta-analysis of associations between MTHFR and GST polymorphisms and susceptibility to multiple sclerosis.

Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology - 1 Nov 2015

Lee Young Ho, Seo Young Ho, Kim Jae-Hoon, Choi Sung Jae, Ji Jong Dae, Song Gwan Gyu

Abstract excerpt

We examined whether methylenetetrahydrofolate reductase (MTHFR) and glutathione S-transferase (GST) polymorphisms are associated with susceptibility to multiple sclerosis (MS). We performed a meta-analysis on the association between MS and the following genotypes: MTHFR C677T, A1298C, and GSTP1 A313G polymorphisms, and GSTM1 and GSTT1 null alleles. Fifteen comparisons involving 2,486 patients and 2,861 controls...

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Share to Genetic Predisposition to Disease
Share to Glutathione S-Transferase pi

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Share to Polymorphism, Genetic

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Source

Identifiers

PMID: 26150166
DOI: 10.1007/s10072-015-2318-7

Genes

MTHFR
GSTM1
GSTP1
GSTT1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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