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Article

Combined GSTP1 and NQO1 germline polymorphisms in the susceptibility to Multiple Sclerosis.

The International journal of neuroscience - 1 Jan 2015

Alexoudi Athanasia, Zachaki Sophia, Stavropoulou Chrysa, Chatzi Ioanna, Koumbi Daphne, Stavropoulou Kalliopi, Kollia Panagoula, Karageorgiou Clementine E, Sambani Constantina

Abstract excerpt

Germline polymorphisms of detoxification genes could influence susceptibility to Multiple Sclerosis (MS). Glutathione-S-transferases (GSTs) and NAD(P)H: quinone oxidoreductase 1 (NQO1) are detoxifying enzymes involved in biotransformation of metabolites preventing cells from oxidative damage. In order to evaluate the possible contribution of the A313G GSTP1 inactivating polymorphism, alone and in combination with...

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Source

Identifiers

PMID: 24588223
DOI: 10.3109/00207454.2014.899597

Genes

GSTP1
NQO1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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