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Article

Association between C677T polymorphism of MTHFR gene and risk of amyotrophic lateral sclerosis: Polish population study and a meta-analysis.

Neurologia i neurochirurgia polska - 1 Jan 2000

Żur-Wyrozumska Kamila, Pera Joanna, Dziubek Anna, Sado Małgorzata, Golenia Aleksandra, Słowik Agnieszka, Dziedzic Tomasz

Abstract excerpt

OBJECTIVE: Genetic factors play a role in pathogenesis of amyotrophic lateral sclerosis (ALS). A few studies demonstrated that the TT genotype of C677T polymorphism of the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene can increase the risk of sporadic ALS. The aim of our study was to determine the relationship between C677T polymorphism of MTHFR gene and the risk of sporadic ALS in Polish population and...

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PMID: 28187987
DOI: 10.1016/j.pjnns.2017.01.008

Genes

MTHFR

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