Article
The glutathione S-transferase T1 deletion is associated with susceptibility to multiple sclerosis.
Journal of the neurological sciences - 15 Nov 2013
Živković Maja, Životić Ivan, Dinčić Evica, Stojković Ljiljana, Vojinović Slobodan, Stanković Aleksandra
Abstract excerpt
BACKGROUND: Multiple sclerosis (MS) occurs as a result of interaction between genetic and environmental factors. Recent data support the view that oxidative damage is one of an early event in MS tissue injury. The safe elimination of reactive oxygen species and toxins via glutathione S-transferase (GST) pathways is required in order to protect cells against reactive oxygen-induced damage. The aim of our study was...
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