Article
Association of Leptin Receptor Gene Polymorphisms with Genetic Susceptibility to Ischemic Stroke.
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association - 1 Sept 2015
Tang Hui, Zhang Zhen, Li Zheng-Ke, Lin Jia, Fang Ding-Zhi
Abstract excerpt
BACKGROUND: Ischemic stroke is a multifactorial disease that is influenced by both genetic and environmental factors. Identification of the genetic factors that are underlining this disease is important. Leptin receptor (LEPR) mediates the leptin-regulated human energy homeostasis, and mutations of LEPR can increase cardiovascular risks and may predispose an individual to ischemic stroke. METHODS: We analyzed...
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