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Article

Association between the Gln223Arg polymorphism of the leptin receptor and metabolic syndrome in free-living community elderly.

Metabolic syndrome and related disorders - 1 Aug 2009

Gottlieb Maria Gabriela Valle, Bodanese Luiz Carlos, Leite Leni Everson Araújo, Schwanke Carla Helena Augustin, Piccoli Jacqueline da Costa Escobar, da Rocha Maria Izabel de Ugalde Marques, da Cruz Ivana Beatrice Manica

Abstract excerpt

BACKGROUND: Metabolic syndrome is a cluster of cardiovascular risk factors. Aging and gene-environmental interactions are involved in the pathophysiology of metabolic syndrome. The LEPR gene Gln223Arg polymorphism has been associated with energy metabolism and body weight. METHODS: The association of the Gln223Arg polymorphism with metabolic syndrome was evaluated in a case-control study with elderly subjects (>...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19344216
DOI: 10.1089/met.2008.0029

Genes

LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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