Article
Role of leptin receptor gene polymorphisms in susceptibility to the development of essential hypertension: a case-control association study in a Northern Han Chinese population.
Journal of human hypertension - 1 Sept 2014
Liu Y, Lou Y Q, Liu K, Liu J L, Wang Z G, Wen J, Zhao Q, Wen S J, Xiao L
Abstract excerpt
In order to explore the potential association between the leptin receptor (LEPR) gene polymorphisms and essential hypertension (EH) risk in the Northern Han Chinese population, we recruited 823 hypertensive subjects and 491 healthy control subjects from the Northern Han Chinese. Genotyping was performed to identify the Lys109Arg, Gln223Arg and Lys656Asn polymorphisms of the LEPR gene. Significant associations...
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