Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Arterial endothelial methylome: differential DNA methylation in athero-susceptible disturbed flow regions in vivo.

BMC genomics - 7 Jul 2015

Jiang Yi-Zhou, Manduchi Elisabetta, Stoeckert Christian J, Davies Peter F

Abstract excerpt

BACKGROUND: Atherosclerosis is a heterogeneously distributed disease of arteries in which the endothelium plays an important central role. Spatial transcriptome profiling of endothelium in pre-lesional arteries has demonstrated differential phenotypes primed for athero-susceptibility at hemodynam...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aorta
Share to Atherosclerosis
Share to CpG Islands

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endothelial Cells

Share to Endothelium, Vascular

Share to Spatio-Temporal Analysis

Share to Transcriptome

Source

Open in PubMed Open full text

Identifiers

PMID: 26148682
DOI: 10.1186/s12864-015-1656-4
PMCID: PMC4492093

Genes

ARHGAP25
ATF4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26148682-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Arterial endothelial methylome: differential DNA methylation in athero-susceptible disturbed flow regions in vivo.PMID 26148682Read ↗

Endothelial epigenetics in biomechanical stress: disturbed flow-mediated epigenomic plasticity in vivo and in vitro.Semantic proximity Read ↗

Emerging topic: flow-related epigenetic regulation of endothelial phenotype through DNA methylation.Semantic proximity Read ↗

Regional determinants of arterial endothelial phenotype dominate the impact of gender or short-term exposure to a high-fat diet.Semantic proximity Read ↗

Mechanosensitive Endothelial METTL7A Regulates Internal m <sup>7</sup> G mRNA Methylation and Protects Against AtherosclerosisSemantic proximity Read ↗

Aortic valve stenosis promotes pathological shear stress-dependent epigenomic dysregulation in circulating T cellsSemantic proximity Read ↗

Epigenetic Induction of Smooth Muscle Cell Phenotypic Alterations in Aortic Aneurysms and Dissections.Semantic proximity Read ↗

Atheroprone Flow Activates SMAD-FOXO1 to drive Endothelial-to-Mesenchymal Transition and AtherosclerosisSemantic proximity Read ↗

Sex-Specific Regulation of Endothelial-to-Mesenchymal Transition (EndMT) During AtherosclerosisSemantic proximity Read ↗

Role of Flow-Sensitive Endothelial Genes in Atherosclerosis and Antiatherogenic Therapeutics Development.Semantic proximity Read ↗

The Complex Role of Methylation in Regulating Vascular Smooth Muscle Cell Phenotypic States in Vascular Remodeling and Atherosclerosis.Semantic proximity Read ↗

Multimodal atlas of human atherosclerosis links granular vascular cell states to coronary artery disease riskSemantic proximity Read ↗

Region-specific gene expression and sex inform about disease susceptibility in the aortaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.